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Akshata Almad

ABOUT ME

Hi! I am a neuroscientist with deep understanding of the role of the non-neuronal cells called 'glial cells' in the central nervous system (CNS) and their interaction with neurons in neurological diseases. My passion is to develop therapeutic treatments for neurological diseases such as Alzheimer's disease, Parkinsons disease and Amyotrophic Lateral Sclerosis.

Research Expertise

  • Glial cells

  • Neurodegeneration

  • Neuron-glial interaction

  • Human stem cell modeling

  • Neuroinflammation

Education

  • PhD in Neuroscience,

      The Ohio State University

  • Masters in Science

       University of Mumbai, India

  • Bachelors in Science,

      University of Mumbai, India

RESEARCH EXPERIENCE

2021-now
Merck
Merck & Co., PA

Senior Scientist, Discovery Neuroscience

Drug discovery expertise on new target Identification, validation, lead optimization and development of translational biomarkers.

In vitro functional cell-based assay and translational animal model PK/PD testing.

2017-2021
CHOP
Children’s Hospital of Philadelphia, PA

Research Associate in Lab of Dr. Adeline Vanderver

Contribution of glial cells, particularly oligodendrocytes and astrocytes, in inherited demyelinating leukodystrophies using transgenic mice and human induced pluripotent stem (iPSC) cells.

2011-17
Johns Hopkins
Johns Hopkins University, Baltimore, MD

Post-doctoral fellow in Lab of Dr. Nicholas Maragakis​

Role of astrocyte connexins in motor neuron toxicity in Amyotrophic Lateral Sclerosis (ALS) using transgenic mouse models and human iPSCs.

2004-11
OSU
The Ohio State  University, Columbus, OH

Graduate student in Lab of Dr. Dana McTigue

Role of PPAR family of transcription factors in oligodendrocyte formation and neuroprotection in context of spinal cord injury. 

NEWS AND ANNOUNCEMENTS

NIH

NINDS R21 grant (2022) and NIH Early Career Reviewer 
Scored 9th percentile and awarded $275,000 
Selected as an ECR program at the Center for Scientific Review at NIH.

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U Penn

Awarded the Transdisciplinary Awards Program in Translational Medicine and Therapeutics grant (2021-23)

Reverse transcriptase inhibition as a novel therapeutic approach for ADAR-1-related Aicardi Goutières Syndrome . 

ULF

United Leukodystrophy Foundation grant (2021-22)
Reverse transcriptase inhibition as a novel therapeutic approach for ADAR-1-related Aicardi Goutières Syndrome . 

NAS

Women in Science Travel Fund grant (2020)
 National Academy of Sciences Pradel Research Award 

Hopkins

Best Oral Presentation and travel award (2016)
Johns Hopkins School of Medicine Postdoctoral Retreat

glia

Post-doctoral fellowship (2013-2015)
Maryland Stem Cell Research Foundation

Teaching fellowship award, Johns Hopkins University (2013)
Notre Dame University of Maryland

The Ohio State University

Society for Neuroscience Graduate Student Chapter Travel Award (2010)
The Ohio State University

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